Comments on: Your DNA, Decoded: 23andMe and Predictive Medicine http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/ a blog about predictive medicine and the future of healthcare Wed, 05 Oct 2011 18:14:44 +0000 hourly 1 http://wordpress.org/?v=3.2.1 By: Aaron http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-689 Aaron Mon, 26 Nov 2007 03:38:02 +0000 http://epidemix.org/blog/?p=223#comment-689 I really like your articles. Most of the paragraphs are so rich that each could be expanded into a full story. I really like your articles. Most of the paragraphs are so rich that each could be expanded into a full story.

]]> By: Mr. Gunn http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-658 Mr. Gunn Mon, 19 Nov 2007 20:13:21 +0000 http://epidemix.org/blog/?p=223#comment-658 No offense, Mr. Goetz. Just kidding around. No offense, Mr. Goetz. Just kidding around.

]]> By: Mr. Gunn http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-654 Mr. Gunn Mon, 19 Nov 2007 02:56:33 +0000 http://epidemix.org/blog/?p=223#comment-654 Excellent point, Attila. See. that's what happens when journalists try to do science. ;-) Excellent point, Attila. See. that’s what happens when journalists try to do science. ;-)

]]> By: GeneticsIsNotAJoke http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-652 GeneticsIsNotAJoke Sun, 18 Nov 2007 11:27:39 +0000 http://epidemix.org/blog/?p=223#comment-652 I do not completely believe in the information about telling you how to live so that you can avoid certain diseases. The truth of the matter is that the exact science to predict such things DOES NOT exits and such speculations could cause a lot of panic among a person’s life. What I mean is that there is no model which exists today, and predicts that if a person has a certain variant in his genome, he/she will get the disease in the future. Even if we assume that such a thing exists, i.e. if someone, somehow is able to test and tell you if you will get a disease in the future, NOTHING much can be done about it. The reason is simple: Pharama companies are not make PRE-Symptomatic drugs, i.e. they are only making drugs for diseases when you show symptoms of those diseases and almost nothing exists for you to take a drug, when you do not have the disease but might get it in the future. I believe such services by 23andme etc are just to increase panic in the world. Having said all this, it is definately a good service to offer, not now, but 10 years or so down the line, when you know exactly how these diseases are caused in the lifetime and when what can be done about them. I hope people really understand what they are doing before opting for such a service. If you have to get a disease in the future, it is better to enjoy your days in life till you get that disease, provided it is a disease for which nothing much can be done about it at this stage. I do not completely believe in the information about telling you how to live so that you can avoid certain diseases. The truth of the matter is that the exact science to predict such things DOES NOT exits and such speculations could cause a lot of panic among a person’s life. What I mean is that there is no model which exists today, and predicts that if a person has a certain variant in his genome, he/she will get the disease in the future. Even if we assume that such a thing exists, i.e. if someone, somehow is able to test and tell you if you will get a disease in the future, NOTHING much can be done about it. The reason is simple: Pharama companies are not make PRE-Symptomatic drugs, i.e. they are only making drugs for diseases when you show symptoms of those diseases and almost nothing exists for you to take a drug, when you do not have the disease but might get it in the future. I believe such services by 23andme etc are just to increase panic in the world. Having said all this, it is definately a good service to offer, not now, but 10 years or so down the line, when you know exactly how these diseases are caused in the lifetime and when what can be done about them. I hope people really understand what they are doing before opting for such a service. If you have to get a disease in the future, it is better to enjoy your days in life till you get that disease, provided it is a disease for which nothing much can be done about it at this stage.

]]> By: Get Your Personal Genome Decoded Here http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-651 Get Your Personal Genome Decoded Here Sun, 18 Nov 2007 09:58:59 +0000 http://epidemix.org/blog/?p=223#comment-651 [...] Thomas Goetz at Wired and Epidemix [...] [...] Thomas Goetz at Wired and Epidemix [...]

]]> By: SonnoProfondo » Blog Archive » Genetica “Retail” http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-650 SonnoProfondo » Blog Archive » Genetica “Retail” Sun, 18 Nov 2007 09:28:35 +0000 http://epidemix.org/blog/?p=223#comment-650 [...] con una vera operatività, come fa notare l’autore dell’articolo su wired sul suo blog, è puramente informativo e in quanto tale non costituisce un servizio di consulenza medica. In [...] [...] con una vera operatività, come fa notare l’autore dell’articolo su wired sul suo blog, è puramente informativo e in quanto tale non costituisce un servizio di consulenza medica. In [...]

]]> By: Attila Csordas http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-648 Attila Csordas Sun, 18 Nov 2007 06:53:51 +0000 http://epidemix.org/blog/?p=223#comment-648 Compelling and pioneering article. One question: From the article: "In its lab, Illumina extracts DNA from saliva and disperses it across a 3- by 1-inch silicon wafer studded with more than 550,000 nanoscopic protein dots. Each dot detects a different SNP; more than half a million dots, strategically distributed across the human genome, cover a meaningful swath of anybody's DNA. I am not familiar with microarray but I wonder whether those are really protein dots on the chip when it is about DNA sequences matched with oligonucleotides so usually in these cases the array contains immobilized nucleic acid sequences? Compelling and pioneering article. One question:

From the article:

“In its lab, Illumina extracts DNA from saliva and disperses it across a 3- by 1-inch silicon wafer studded with more than 550,000 nanoscopic protein dots. Each dot detects a different SNP; more than half a million dots, strategically distributed across the human genome, cover a meaningful swath of anybody’s DNA.

I am not familiar with microarray but I wonder whether those are really protein dots on the chip when it is about DNA sequences matched with oligonucleotides so usually in these cases the array contains immobilized nucleic acid sequences?

]]> By: » Your personal health: Consumer genomics becomes reality » business|bytes|genes|molecules http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-647 » Your personal health: Consumer genomics becomes reality » business|bytes|genes|molecules Sun, 18 Nov 2007 00:05:19 +0000 http://epidemix.org/blog/?p=223#comment-647 [...] Reading Epidemix ScienceRoll Berci reviews personal genetics companies A cautionary [...] [...] Reading Epidemix ScienceRoll Berci reviews personal genetics companies A cautionary [...]

]]> By: 23andMe Launches Their Personal Genome Service » The Genetic Genealogist http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-646 23andMe Launches Their Personal Genome Service » The Genetic Genealogist Sat, 17 Nov 2007 19:03:39 +0000 http://epidemix.org/blog/?p=223#comment-646 [...] Goetz, the author of the piece in Wired, wrote a post about the experience in his blog Epidemix (a fellow blog from The DNA Network). Mr. Goetz’s [...] [...] Goetz, the author of the piece in Wired, wrote a post about the experience in his blog Epidemix (a fellow blog from The DNA Network). Mr. Goetz’s [...]

]]> By: Blaine http://thedecisiontree.com/blog/2007/11/your-dna-decoded-23andme-and-predictive-medicine/comment-page-1/#comment-645 Blaine Sat, 17 Nov 2007 17:55:30 +0000 http://epidemix.org/blog/?p=223#comment-645 Thomas, I thought you did a great job introducing the reader to the company and to the major players, as well as many of the thorny issues associated with genomic testing. It sounds like it was quite an experience. And I'm also sorry that you never got to meet your grandfather. Thomas,

I thought you did a great job introducing the reader to the company and to the major players, as well as many of the thorny issues associated with genomic testing. It sounds like it was quite an experience. And I’m also sorry that you never got to meet your grandfather.

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